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Invoice Statistician in Japan Tokyo –Free Word Template Download with AI

2-14-8 Roppongi, Minato-ku, Japan Tokyo 106-0032

Tel: +81-3-5412-7890 | Email: [email protected]

Corporation Number: 4010401023456

Representative: Dr. Kenji Tanaka, Chief Statistician

Invoice No.: QASC-2025-0487

Date Issued: June 15, 2025

Due Date: July 15, 2025

Service Period: April 1 – May 31, 2025

JAPAN TOKYO

Bill To (Client)

Shinsei Pharmaceutical Research Institute

Attn: Mr. Hiroshi Yamamoto, Director of Data Science

7-22-1 Meguro, Meguro-ku, Japan Tokyo 153-0063

Tel: +81-3-3712-4567

Email: [email protected]

Client Reference: SPR-2025-STAT-009

Service Provider

Dr. Kenji Tanaka, Ph.D. (Statistics)

Lead Statistician, Quantum Analytics & Statistical Consulting

Licensed Statistician, Japan Society of Statistics (JSS)

Registration No.: JSS-2019-00482

Office: Roppongi Business Center, 12F

Japan Tokyo, Minato-ku

# Description of Statistical Services Rate (JPY) Hours Amount (JPY) Date Performed
1 Comprehensive biostatistical analysis of Phase II clinical trial data for novel oncology compound. The Statistician performed survival analysis, hazard ratio estimation, and confidence interval calculations in accordance with ICH E9 guidelines. ¥45,000 48 ¥2,160,000 Apr 3 – Apr 25, 2025
2 Design and implementation of a mixed-effects model for longitudinal patient response data. The Statistician developed the model specification, conducted power analysis, and validated model assumptions using diagnostic plots and residual analysis. ¥45,000 36 ¥1,620,000 Apr 28 – May 12, 2025
3 Preparation of the statistical analysis plan (SAP) document for the upcoming Phase III trial. This Invoice item covers the full drafting, internal review, and revision of the SAP in collaboration with the client's regulatory affairs team in Japan Tokyo. ¥50,000 40 ¥2,000,000 May 5 – May 22, 2025
4 Bayesian statistical modeling and posterior probability estimation for adaptive trial design. The Statistician utilized MCMC methods and conducted sensitivity analyses on prior distributions to support interim decision-making. ¥50,000 32 ¥1,600,000 May 13 – May 28, 2025
5 On-site consultation and presentation of statistical findings to the executive board at the client's headquarters in Japan Tokyo. Includes preparation of visual dashboards, interactive R Shiny applications, and a 90-minute Q&A session with senior management. ¥60,000 12 ¥720,000 May 30, 2025
6 Statistical data audit and quality assurance review of the clinical trial database. The Statistician verified data integrity, checked for protocol deviations, and produced a comprehensive audit trail report for regulatory submission. ¥40,000 24 ¥960,000 May 20 – May 31, 2025

Subtotal:¥9,060,000

Consumable Materials & Software Licenses:¥185,000

Travel & Local Transport (Japan Tokyo Metro Area):¥42,000

Consumption Tax (10%):¥928,700

TOTAL DUE:¥10,215,700

Payment Instructions

Bank: Mizuho Bank, Roppongi Branch, Japan Tokyo

Account Name: Quantum Analytics & Statistical Consulting Co., Ltd.

Account Number: 012-3-456789 (Ordinary Savings)

SWIFT Code: MHCBJTJT

Reference: Please cite Invoice No. QASC-2025-0487 in all payment communications.

Payment Method: Bank transfer (domestic) or international wire transfer. Payment is due within 30 days of the Invoice issue date. Late payments will incur a penalty of 1.5% per month as stipulated under Japanese Commercial Code Article 547.

Important Notes & Terms

This Invoice is issued in accordance with the Service Agreement dated March 1, 2025, between Quantum Analytics & Statistical Consulting Co., Ltd. and Shinsei Pharmaceutical Research Institute. All statistical work performed by the Statistician was conducted in full compliance with the Japanese Pharmaceutical and Medical Devices Act (PMDA regulations) and applicable ICH guidelines.

  • All statistical analyses were performed using R (v4.3.2), SAS (v9.4), and Python (v3.11) in a validated computational environment.
  • The Statistician certifies that all methodologies, assumptions, and results presented in the deliverables are accurate and reproducible.
  • Confidentiality obligations under the Non-Disclosure Agreement (NDA-2025-012) remain in full effect. All raw data and intermediate files will be securely archived for a minimum of 15 years in Japan Tokyo as required by PMDA regulations.
  • This Invoice is valid for 90 days from the date of issue. Please contact our billing department in Japan Tokyo for any discrepancies or questions regarding the line items above.
  • Disputes, if any, shall be resolved through mediation in the Tokyo District Court, Japan Tokyo, in accordance with Japanese civil law.

Quantum Analytics & Statistical Consulting Co., Ltd. | 2-14-8 Roppongi, Minato-ku, Japan Tokyo 106-0032

Corporation No. 4010401023456 | Representative: Dr. Kenji Tanaka | Tel: +81-3-5412-7890

This Invoice was generated electronically and is valid without a physical signature. For verification, contact [email protected].

© 2025 Quantum Analytics & Statistical Consulting Co., Ltd. All rights reserved. | Invoice QASC-2025-0487 | Japan Tokyo

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